diff --git a/core/admin/mailu/internal/templates/default.sieve b/core/admin/mailu/internal/templates/default.sieve
index f08c19bb..c1772c2e 100644
--- a/core/admin/mailu/internal/templates/default.sieve
+++ b/core/admin/mailu/internal/templates/default.sieve
@@ -35,5 +35,7 @@ if exists "X-Virus" {
 }
 
 {% if user.reply_active %}
-vacation :days 1 {% if user.displayed_name != "" %}:from "{{ user.displayed_name }} <{{ user.email }}>"{% endif %} :subject "{{ user.reply_subject }}" "{{ user.reply_body }}";
+if not address :localpart :contains ["From","Reply-To"] ["noreply","no-reply"]{
+  vacation :days 1 {% if user.displayed_name != "" %}:from "{{ user.displayed_name }} <{{ user.email }}>"{% endif %} :subject "{{ user.reply_subject }}" "{{ user.reply_body }}";
+}
 {% endif %}
diff --git a/towncrier/newsfragments/2823.bugfix b/towncrier/newsfragments/2823.bugfix
new file mode 100644
index 00000000..883e0d75
--- /dev/null
+++ b/towncrier/newsfragments/2823.bugfix
@@ -0,0 +1 @@
+Don't send out of office messages to no\-?reply@